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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC2H1
All Species:
16.97
Human Site:
T2259
Identified Species:
37.33
UniProt:
Q8NCM8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCM8
NP_001073932
4307
492594
T2259
D
D
F
S
N
G
L
T
L
P
V
I
Q
T
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536596
4306
491933
T2259
D
D
F
N
N
G
Q
T
L
P
V
I
Q
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q45VK7
4306
492321
I2259
D
D
F
S
N
G
H
I
L
P
V
I
Q
T
P
Rat
Rattus norvegicus
Q9JJ79
4306
492200
S2259
D
D
F
S
S
G
H
S
L
P
V
I
Q
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509757
4391
500194
T2350
E
D
F
N
N
I
Q
T
L
P
V
I
Q
T
P
Chicken
Gallus gallus
XP_417173
4301
491979
T2256
D
N
F
S
N
L
Q
T
L
P
V
I
Q
I
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37276
4639
530166
D2490
V
L
W
S
F
A
G
D
A
K
L
K
V
R
I
Honey Bee
Apis mellifera
XP_395108
4023
452032
S2084
D
T
D
D
G
P
V
S
L
S
G
D
M
K
R
Nematode Worm
Caenorhab. elegans
Q19542
4171
473799
L2194
E
E
V
E
R
E
D
L
R
P
F
V
Q
T
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36022
4092
471329
D2157
I
W
V
V
F
D
S
D
L
D
P
E
Y
V
E
Red Bread Mold
Neurospora crassa
P45443
4367
495560
I2498
P
E
Q
V
E
G
Y
I
A
K
K
V
L
L
A
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.5
N.A.
93.3
93
N.A.
85.8
79.7
N.A.
N.A.
N.A.
26.4
30.3
40.7
N.A.
Protein Similarity:
100
N.A.
N.A.
96.5
N.A.
97.1
97
N.A.
91.8
89.4
N.A.
N.A.
N.A.
47.8
52.5
61.2
N.A.
P-Site Identity:
100
N.A.
N.A.
80
N.A.
86.6
80
N.A.
73.3
73.3
N.A.
N.A.
N.A.
6.6
13.3
20
N.A.
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
86.6
93.3
N.A.
86.6
80
N.A.
N.A.
N.A.
20
26.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.8
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
19
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
46
10
10
0
10
10
19
0
10
0
10
0
0
0
% D
% Glu:
19
19
0
10
10
10
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
0
55
0
19
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
46
10
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
19
0
0
0
55
0
19
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
19
10
10
0
10
0
% K
% Leu:
0
10
0
0
0
10
10
10
73
0
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
19
46
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
10
0
0
0
64
10
0
0
0
55
% P
% Gln:
0
0
10
0
0
0
28
0
0
0
0
0
64
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
10
0
0
0
0
10
10
% R
% Ser:
0
0
0
46
10
0
10
19
0
10
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
37
0
0
0
0
0
46
0
% T
% Val:
10
0
19
19
0
0
10
0
0
0
55
19
10
10
0
% V
% Trp:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _